Generally benign papilloma that arises from the stratified squamous epithelium
Aetiology
- Two peaks of incidence - <5 years and between 20-40 years
- Related to HPV exposure - types 6 and 11
- Children - aggressive disease
Clinical presentation
- Painless lesion most commonly found in the mucosa of the hard and soft palate
- Commonly involves soft palate, tongue, lips, tonsils but can occur anywhere there is stratified squamous epithelium (e.g. skin, oesophagus, cervix)
Investigations
Biopsy
- Macroscopic - exophytic, sessile or pedunculated mass
- Microscopic - finger-like projection, fibrovascular core covered by stratified squamous epithelium
Management
- Most cases require no treatment
- When treatment required, options include cryotherapy, topical salicylic acid and surgical excision