Trigeminal Autonomic Cephalgias

Primary headache syndromes characterized by severe short-lasting headaches accompanied by paroxysmal facial autonomic symptoms

Clinical presentation

  • Headache
  • Autonomic features include: ptosis, miosis, nasal stuffiness, nausea/vomiting, tearing, eye lid oedema

Investigations

  • Those with new onset unilateral cranial autonomic features require imaging - MRI brain and MR angiogram

Cluster headache

  • More common in 30s-40s, more common in men

Clinical features

  • Recurrent attacks of sudden-onset unilateral periorbital pain, associated with a watery and bloodshot eye, lacrimation, rhinorrhoea, miosis, ptosis, lid swelling, and facial flushing
  • Headaches last 15 minutes to 3 hours, occur once or twice a day, over a period of 4-12 weeks, and are followed by a pain-free period of months before the next cluster begins

Management

  • Acute attack: high flow O2 100% for 20 mins with a subcutaneous or nasal triptan, steroids (reducing course over 2 weeks)
  • Prophylaxis: verapamil

Paroxysmal hemicrania

  • More common in 50s-60s, more common in women

Clinical features

  • Severe unilateral headache
  • Unilateral autonomic features
  • 10-30 mins duration
  • 1-40 a day

Management

  • Absolute response to indomethicin

Hemicrania continua

  • More common in 50s-60s, more common in women

Clinical features

  • Severe unilateral headache
  • Unilateral autonomic features
  • Constant duration

Management

  • Absolute response to indomethicin

SUNCT

  • Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing

Clinical features

  • Unilateral neuralgiaform headache
  • Short-lived (15-120 secs)
  • Conjunctival injections
  • Tearing

Management

  • Lamotrigine
  • Gabapentin