Both the number of people affected by malnutrition and highest prevalence of wasting occur in lower-middle-income countries
Aetiology
- Lack of access
- Poor feeding practices
- Infection
Clinical presentation

Kwashiorkor - protein energy malnutrition from only having carbs resulting in oedema

Marasmus - characterized by energy deficiency resulting in low body weight
Investigations
Diagnosis of severe acute malnutrition (kwashiorkor or marasmus)
- Mid-arm circumference <115mm
- Weight for height under 3SD
- Oedema of both feet
Management
Criteria for inpatient or outpatient care
- Children who are identified as having severe acute malnutrition should first be assessed with a full clinical examination to confirm whether they have medical complications and whether they have an appetite
- Children who have appetite and are clinically well and alert should be treated as outpatients
- Investigate cause
- Vitamin A
- De-worm
- Ready to use therapeutic food (RUTF) - peanut butter, dried milk, vitamins and minerals
- Check vaccinations
- Children who have medical complications, severe oedema, or poor appetite or present with one or more danger signs should be treated as inpatients (as below)
Inpatient management
- Management is the same for kwashiorkor and marasmus
- Involves 10 steps in 2 phases - initial stabilisation and rehabilitation

- All severely malnourished children are at risk of hypoglycaemia - give a feed or 10% glucose/sucrose immediately on admission
- All children with hypothermia should be treated routinely for hypoglycaemia and infection
- Dehydration tends to be overdiagnosed - do not use IV route for rehydration except in shock, rehydrate slowly (orally or NG tube) with a special rehydration solution for malnutrition ReSoMal (ORS not suitable for severely malnourished children)
- Early iron aggregates infection so avoided until rehabilitation phase
- Keep breastfeeding if able but also initiate feeding with F75 milk then catch up with F100