Neonatal Abstinence Syndrome

Refers to the withdrawal symptoms that happens in neonates of mothers that used substances in pregnancy

Aetiology

Substances that cause NAS

  • Opiates
  • Methadone
  • Benzodiazepines
  • Cocaine
  • Amphetamines
  • Nicotine or cannabis
  • Alcohol
  • SSRI antidepressants

Clinical presentation

  • CNS: irritability, tremors, seizures
  • Vasomotor and respiratory: sweating, unstable temperature, tachypnoea
  • Metabolic and GI: poor feeding, regurgitation/vomiting, hypoglycaemia

Management

  • Mothers that are known to use substances should have an alert on their notes so that when they give birth the neonate can have extra monitoring and management of NAS
  • Babies are kept in hospital with monitoring on a NAS chart for at least 3 days (48 hours for SSRI antidepressants) to monitor for withdrawal symptoms
  • The neonate should be supported in a quiet and dim environment with gentle handling and comforting
  • Medical treatment options are avaliable for moderate to severe symptoms